1 Litre of Tears Miniseries Episode 4 Two Loneliness ( Air Date 2005-11-01 ) Genre Drama, Family category. Overview "Aya is told by Dr. Mizuno, a neurologist at Jounan University Hospital, that she has spinocerebellar degeneration. Returning home with her mother, Shioka, Aya tries to force a smile and act brave, but she is unable to accept her illness and begins to cry.".